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· wt1 is a tumor suppressor gene associated with the development of wilms tumor, from which it was named. Mutations in exon 7 and 9 of wt1 have been recurrently identified in … The active enzyme is a homotetramer arranged … · this gene encodes a nuclear-localized e3 ubiquitin ligase. · this gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. Function, proteins, disorders, pathways, … Function, proteins, disorders, pathways, orthologs, and … The genecards human gene database index: Geneanalytics enables researchers to identify diseases related to their gene sets, and to discover disease mechanisms and specific disease markers. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal … In this system, … · the knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. Geneanalytics disease-related outputs … · this gene encodes pyruvate carboxylase, which requires biotin and atp to catalyse the carboxylation of pyruvate to oxaloacetate. Function, proteins, disorders, pathways, orthologs, and expression. · complete information for map4k4 gene (protein coding), mitogen-activated protein kinase kinase kinase kinase 4, including: · complete information for ass1 gene (protein coding), argininosuccinate synthase 1, including: · complete information for gapdh gene (protein coding), glyceraldehyde-3-phosphate dehydrogenase, including: