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· rugae are anatomical folds or ridges found in the inner lining of certain organs. These ridges are composed of mucous membrane and underlying connective tissue. In the absence of food, the stomach deflates inward, and its mucosa and submucosa fall into large folds called rugae. What does rugae mean? Plural rugae -ˌgī -ˌgē -ˌjē : Most commonly rugae refers to the gastric rugae of the internal surface of the stomach. The cardia, fundus, body, and pylorus. Figure 23. 4. 1 – stomach: These temporary structures appear when an organ is relaxed or empty, flattening out as it distends or fills. Rugae develop during fetal growth and are present at birth in regions like the stomach and hard palate. Meaning of rugae medical term. In general, rugae are a biological feature found in many organisms, serving purposes such as increasing surface area, flexibility, or structural support. An anatomical fold or wrinkle especially of the viscera usually used in plural the rugae of an empty stomach When the vagina is relaxed, these folds are prominent, allowing the walls to maintain a wrinkled … The number and size of rugae can vary between individuals and can change over time due to factors like age, pregnancy, or diseases affecting the mucosa. The stomach has four major regions: