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· zofran (ondansetron) is used to prevent nausea and vomiting caused by surgery or cancer medicines. Read the latest news and reviews about the drug as well as potential … Zofran® (ondansetron) is a medication that prevents nausea and vomiting caused by chemotherapy, radiation or surgery. · ondansetron blocks a specific receptor in the gut (intestines) and brain called 5-ht 3 that normally causes nausea and … Medscape - nausea & vomiting dosing for zofran (dsc) (ondansetron), frequency-based adverse effects, comprehensive interactions, … Includes zofran side … · learn about ondansetron (zofran) usage and dosing.